Thermo Fisher Scientific
Inc., the world leader in serving science, today announced the launch of
the Thermo Scientific ToxSpec(TM) Analyzer, a complete, easy-to-use and cost-effective
LC-MS solution for clinical and forensic toxicology-screening laboratories.
Using an integrated system of hardware, software and methodologies, the ToxSpec
Analyzer dramatically simplifies the toxicology workflow by automating the screening
of drug analytes, increasing confidence of identification and enabling even
a novice user to generate reliable results.
“The ToxSpec Analyzer is another example of Thermo Fisher taking high-performance
technology that has been limited to the research lab and making it accessible
to applied markets as a complete, turnkey solution,” said Jeff Zonderman,
director, Thermo Fisher Scientific life science mass spectrometry clinical and
toxicology markets. “Even if your lab has never used LC/MS/MS, this solution
is designed to make it easy for you to get up and running. The ToxSpec Analyzer
provides industry-leading instrumentation for higher sensitivity and specificity,
ready-to-use software and methodologies and an extremely competitive price point.
Bio-Rad’s REMEDi is a great example of a drug screening application that
this solution very nicely replaces.”
The ToxSpec Analyzer includes a tested screening workflow methodology that
covers every step of screening from sample preparation to analysis, data processing
and reporting. The ToxSpec Analyzer CD includes:
- SPE sample preparation method
- LC-MS data acquisition method
- Compound library
- ToxID software configuration
- List of recommended consumables
Robert D. Johnson, Ph.D., a research chemist with the Federal Aviation Administration
Civil Aerospace Medical Institute, has been successfully using the ToxID 1.0
software, which is part of the ToxSpec Analyzer product, for the past eight
months for general unknown screening.
"ThermoFisher Scientific's ToxID software is well designed, user friendly,
and has made our laboratories goal of performing general unknown screening by
LC/MS obtainable," said Dr. Johnson.
Every aspect of the ToxSpec Analyzer has been designed to ensure maximum ease-of-use
and flexibility. The ToxID software requires only an initial configuration;
it then integrates behind the scenes and is automatically implemented by the
data acquisition software for compound identification and report generation.
The ToxID software can generate summary and data review reports in PDF format
as well as Excel reports, depending on lab needs.
Although it is simple to operate, the ToxSpec Analyzer meets the most exacting
lab performance standards. Thermo Fisher Scientific qualified the screening
application in a urine matrix for all compounds in the spectra library and the
list of analytes with confirmed detection limits is included.
Using the ToxSpec Analyzer LC-MS approach to toxicology screening also provides
researchers with more flexibility than traditional approaches. With the ToxSpec
Analyzer, researchers can add new compounds to the application as needed, a
huge benefit as new drugs are discovered.
For more information on the Thermo Scientific ToxSpec Analyzer, as well as
other Thermo Scientific products, please call +1 800-532-4752.
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