Understanding a Fine Chemical

Fine chemicals are inorganic or organic molecules produced in kilogram to multi-ton quantities by conventional or biotechnological chemical processes in plants across the world. They are manufactured to rigorous specifications and serve as crucial components of the value chain for downstream applications, including many day-to-day products relied upon by consumers. The developing and manufacturing process of fine chemicals is complex and usually subject to multi-step synthesis.

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Fine Chemical Applications

The largest consumer of fine chemicals is the pharmaceutical industry, as several starting materials, advanced intermediates and active ingredients are sourced from a mixture of fine chemical manufacturing partners, producing life-saving treatments and medicines.

Similarly, fine chemicals are also employed in the agrochemical industry for manufacturing pesticides, fungicides, and herbicides through rigorously controlled contamination prevention protocols. Agrochemicals are important to enhance yields and harvests of produce to feed the world’s increasing population.

Other applications that involve the use of fine chemicals include catalysts, adhesives, food, and specialty polymers for advanced composites, foams, fibers, and electronic components. The performance of smartphone technology is attributed to the high-purity of fine chemical intermediates.

Fine Chemical Technologies

The development and manufacture of fine chemicals involve a number of different technologies, because of the challenging nature of their production. Azo chemistry, Alkylation, Grignard chemistry, Formylation, Heterocyclic synthesis, Halogenation, Suzuki coupling, Phosphorous chemistry and Hydrogenation are but a few of the competencies required for a full-service manufacturer to support applications in multiple industries.

Fine Chemicals from CABB

CABB Group GmbH has a wealth of experience in the development and production of fine chemicals, offering a portfolio of made-to-order products, used as raw materials in a variety of applications.

CABB also provides fine chemical custom manufacturing services, and its team is readily available to help clients assess their make-or-buy options.

CABB’s sourcing solutions are high in value, efficacy, and quality.

For more information about the array of fine chemicals, customers can contact CABB.

Understanding a Fine Chemical

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In the manufacture of custom chemicals, CABB specializes in a range of chemistries, which provide customers with a high-quality and cost-efficient product. The following sections some of the key chemistries used by CABB.


Alkylation is the process in which an alkyl group is transferred from one molecule to another to develop a custom chemical. Alkylation can be classified into two, based on the alkylating agent.

A nucleophilic alkylating agent delivers a negatively charged alkyl group to the hydrocarbon, which is the equivalent of an alkyl anion. Examples of these include Grignard reagents, organocopper, and organolithium.

An electrophilic alkylating agent delivers a positively charged alkyl group to the hydrocarbon, which is the equivalent of an alkyl cation. Alkyl halides are typical electrophilic alkylating agents.


Halogenation is the process in which a halogen is added to a compound or material in order to develop a custom chemical.

Several techniques are available to perform halogenation that can differ by halogen type; fluorination, chlorination, etc. or due to reaction type; halogenation of aromatic compounds, free radical halogenation, etc.

The method used to perform halogenation can be determined by the structure of the substrate and the halogen agent used.

Grignard Chemistry

The Grignard reaction is characteristically used for the formation of carbon-carbon bonds. It consists of the reaction between a Grignard reagent (organomagnesium halide) and a wide range of compounds such as aldehydes, ketones, alkyl halides, and esters.

Suzuki Coupling

Suzuki coupling is a metal catalyzed (often Pd or Pt) reaction between an organohalide and a boronic acid or ester. This chemistry is often used to synthesize poly-olefins, styrenes, and usually substituted biphenyls.


Hydrogenation is defined as the chemical reaction that takes place between hydrogen and another element, often using a catalyst such as platinum or palladium. It is generally used in the conversion of unsaturated compounds to saturated derivatives.

Custom Chemicals from CABB

CABB specializes in developing and manufacturing a range of custom chemicals for customers using an array of various chemistries and technologies. CABB’s services team is always available to provide assistance to customers evaluating their make-or-buy options.

For more information about CABB’s range of custom chemicals, customers can contact the company.

This information has been sourced, reviewed and adapted from materials provided by CABB Group GmbH and Nexam Chemical AB.

For more information on this source, please visit CABB


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