The existence of small concentrations of large particles is critical to the quality of different types of nanoparticle dispersions. These large particles can indicate that dispersion is unstable or will clog filters. The determination of large particle concentrations can be performed in the quality control lab using the Accusizer 780 AD or the 780 APS.
An unsuccessful product will have to be sent back to the factory floor for additional processing or would be discarded. In this process, both money and time are lost.
The 780 OL system from Particle Sizing Systems, An Entegris Company can be used for efficient in-process monitoring. The 780 Point-of-Use (POU) monitor is the latest addition to the 780 Online family. It is a compact and low-cost unit suitable for applications that need little or no dilution. The 780 POU, besides having systems for handling concentrated dispersions like inks or emulsions, combines the monitoring of contamination that will have a greater effect on pharmaceutical PAT.
The main features of the AccuSizer 780 Online analyzer are:
- Comprises a mixture of tools for various in-process and online applications
- Represents a variety of Autodilution fluidics that can be selected for optimal measurement
- Can be used for monitoring processes from homogenization to grinding to semiconductor CMP polishing.