Lenterra Sensors - Sensors for In-Line, Real-Time Flow Measurements

Freeman Technology are the worldwide exclusive distributors of Lenterra products.

Lenterra Flow Sensor (LFS) System

The Lenterra Flow Sensor (LFS) System consists of a Drag Force Flow (DFF) sensor, the Lenterra Optical Interrogator (LOI) and a ruggedised laptop with bespoke software.

The system provides an in-line, real-time assessment of powder flow enabling improvements in process understanding and manufacturing efficiency in various industries.

Key Features

  • Real-time, in-line measurement of material properties and temperature
  • Fibre optic connectivity
  • Multi-directional sensitivity
  • Chemically resistant construction

Benefits

  • Robust Process Analytical Technology (PAT)
  • Optimize cycle times
  • Enhance consistency and product quality
  • Improve process understanding
  • Simplify or accelerate scale up
  • Enhance compliance
  • Reduce 'out of specification' rework and material
  • Minimize costs related to resample, retesting, reworks, etc.

Lenterra Flow Sensor (LFS) System

The Lenterra Flow Sensor (LFS) System  consists of a Drag Force Flow (DFF) sensor, the Lenterra Optical Interrogator (LOI) and a ruggedised laptop with bespoke software.

The system provides an in-line, real-time assessment of powder flow enabling improvements in process understanding and manufacturing efficiency in various industries.

Download the LFS Brochure Here

How it Works

The DFF sensor consists of a hollow pillar mounted on a stationary base, containing two optical strain gauges, Fibre Bragg Gratings (FBGs). The LOI is connected to the FBGs via a fibre optic cable and continuously monitors the FBG spectra. When the pillar is deflected by flow, one FBG becomes extended and the other one is compressed, leading to a shift in wavelength spectra. A larger deflection results in a greater shift.

When the probe is immersed in a moving powder or material, the DFF sensor bends under the force of the flow. The magnitude of the deflection is continuously measured and quantifies the drag force in real-time, which is a function of material properties such as size, density, adhesion and strength, allowing operators to assess material properties in-process.

Cross section of a DFF sensor

The technical support from Freeman Technology is super. You can expect responses within 24 hours.

Dr Shau Yen, Senior Fellow, Novartis Pharma AG

Applications

  • High Shear Wet Granulation
  • Drying or spray drying
  • Feeding
  • Blending
  • Flow rates in transfer chutes and pipes

Case Study - High Shear Wet Granulation

High Shear Wet Granulation (HSWG) is widely employed in many industries. Effective management of HSWG processes requires an understanding of granule evolution and the impact of changing properties. The DFF sensor delivers valuable information to assist formulation and process development, as well as for routine monitoring, control during manufacturing, and scale-up strategy. The data below illustrates how the technology can be used to robustly track a granulation process, enabling the user to monitor granule evolution without disrupting the process.

Advantages of Drag Force Flow (DFF) Sensors:

  • Ability to assess properties of the granulated wet mass without halting the process
  • Measured FPM signal relates to wet mass consistency and granule  densification, delivering significantly more information than granule size distribution alone
  • Determine the effect of process parameters on granule properties (e.g. impeller speed/time, water content)
  • Able to identify and quantify minor batch-to-batch variations with comparable formulations
  • Accurately track each stage of granulation process Can be used to define granulation end-point – enabling robust formulation development as well as process design and control Supports efficient scale-up of wet granulation processes

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