3D Terahertz Imaging Systems for Tablet Coatings and Cores

The 3D Terahertz Imaging Systems are an addition to the TeraPulse 4000 product-range. It has been enhanced for non-destructive determination of the performance and integrity of finished tablet coatings and cores, and other solid dosage forms.

Centered upon TeraView’s proprietary semiconductor-based THz pulsed technology and more than 70 patented technologies and processes, the system yields full 360° imaging of total tablet coatings and cores. It is based on a decade of experience in tablet imaging collected through work with TeraView customers and collaborators.

The system offers THz image analysis which allows users to establish the uniformity, thickness, density and coverage of simple and complex coatings and to identify structural features such as dislocations, cracks, and delaminations in single and multilayer cores.

Product Features

  • Non-destructive 3D volumetric imaging of solid dosage forms
  • Offers critically informative data on coating, solid dosage core, and interfacial structures
  • Mapping of thickness and density uniformity of numerous coating layers and bilayer cores
  • Modular: part of TeraPulse series of modules

Technical Specification

THz pulsed system
Terahertz source Proprietary laser gated photo-conductive semiconductor emitter
Terahertz detector Proprietary laser gated photo-conductive semiconductor receiver
Spectral range 0.06 THz – 4 THz (10 cm-1 – 133 cm-1)
3D THz image analysis - Spatial resolution
At surface 160 μm @ 2.58 THz
3D THz image analysis - Layer thickness resolution
Near surface 30 μm
Layer thickness precision 2 μm
Penetration depth 3 mm (typical), larger penetration possible, material dependent
Sample size 5 – 20 mm
Data point interval Point-to-point: 50 – 500 μm, user selectable
Continuous scan: 200 μm nominal
Image acquisition rate
(depends on surface area)
5 mm x 10 mm diameter circular biconvex tablet with center band
Point-to-point: 32 min (@ 200 μm)
Continuous scan: 22 min
Integrated computer
Network/data transfer External USB port
Environmental - Robotic sampling system
Dimensions 1000 mm (w) x 1000 mm (d) x 1950 mm (h)
Power requirements 90 to 250 VAC, 47 to 63 Hz single phase
Compressed air supply 90 psi (6 bar) supply line, up to 175 L/minute
Location requirements within 0.5 m (20 in) of TeraPulse 4000
Operating temperature 18 °C (64 °F) – 30 °C (86 °F)
Operating humidity 20 - 80% (non-condensing)
Environmental
Dimensions 702 mm (w) x 645 mm (d) x 468 mm (h)
Weight 70 kg
Power requirements 90 to 250 VAC, 47 to 63 Hz single phase
Power consumption 300 VA
Operating temperature* 18 °C (64 °F) – 30 °C (86 °F)
Operating humidity 20 – 80% (non-condensing)

*For best performance during long-term measurements, ambient temperature variations must not exceed 1 °C (0.8 °F) in a 1-hour period and 2 °C (3.6 °F) over an 8 hour period.

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