Latest Materials Articles RSS Feed - Materials Articles

Polymer Analysis Using Raman Spectroscopy

Polymer Analysis Using Raman Spectroscopy

For the past several years, vibrational spectroscopy has been utilized for polymer analysis, and IR spectroscopy is the traditionally preferred method. Nevertheless, recent technological developments have made Raman spectroscopy more user friendly and economical when compared to the past. [More]
Raman Monitoring of Polymorph Transformation in High Shear Wet Granulation Using Kaiser’s Raman Analyzer

Raman Monitoring of Polymorph Transformation in High Shear Wet Granulation Using Kaiser’s Raman Analyzer

In pharmaceutical manufacturing, granulation is a key process to optimize a powder mixture’s tableting properties, such as blend uniformity, compactibility, and flowability. Wet granulation involves subjecting a physical mixture of API and excipients to shear in a granulating solution which serves a binder for the tablet. [More]
Using Kaiser’s RamanRxn™ Analyzer for Monitoring of Blend Uniformity of Granules Prior to Tablet Press

Using Kaiser’s RamanRxn™ Analyzer for Monitoring of Blend Uniformity of Granules Prior to Tablet Press

The Process Analytical Technology (PAT) initiative of the FDA helps pharmaceutical companies to improve the production process and consistently deliver products of better quality. For this purpose, it is essential to have instruments capable of monitoring pharmaceutical unit operations in real time to gain insights and control key process parameters. [More]
Polymorphic Identification Using Raman Microscopy

Polymorphic Identification Using Raman Microscopy

Polymorphism is common in all organic molecules, forming more than one unique crystalline forms called polymorphs. This phenomenon is gaining traction especially in the pharmaceutical industry owing to the fact that a compound’s different polymorphs exhibit different physical and chemical properties, including bioavailability, dissolution rate, and thermal stability. [More]
Using Kaiser’s RamanRxn2™ Analyzer to Monitor Emulsion Polymerization Reactions

Using Kaiser’s RamanRxn2™ Analyzer to Monitor Emulsion Polymerization Reactions

A range of polymeric materials such as synthetic rubbers, adhesives, and paints have been produced using emulsion polymerization, which is carried out in an aqueous environment. [More]
Monitoring and Control of a Semi-Batch Polymerization with Raman Spectroscopy from Kaiser Optical Systems

Monitoring and Control of a Semi-Batch Polymerization with Raman Spectroscopy from Kaiser Optical Systems

When compared to conventional batch reactions, reactions in semi-batch mode offer better product selectivity, the ability to gradually add reactants for greater control of the process and the possibility of isolating product subsequent to its formation. [More]
Using RamanRxn1™ from Kaiser Optical Systems for Microstructural Analysis of Polybutadienes

Using RamanRxn1™ from Kaiser Optical Systems for Microstructural Analysis of Polybutadienes

One of the most widely used industrial polymers is polybutadienes, representing more than 2 billion pounds of plastics and more than 4 billion pounds of rubber annually. The superior resiliency of polybutadienes makes them suitable for high-stress applications, including the cores of golf balls and the sidewalls and treads of tires. [More]
Analyzing the Kinetics of a Catalytic Hydrogenation Reaction Using the RamanRxn2™ Analyzer from Kaiser Optical Systems

Analyzing the Kinetics of a Catalytic Hydrogenation Reaction Using the RamanRxn2™ Analyzer from Kaiser Optical Systems

Most industrial processes are based on catalytic hydrogeneation, including the hydrogenation of different unsaturated compounds, aromatics, and olefins, and the catalytic reduction of nitro compounds to amino compounds. Most nitro-reduction reactions involve the use of a heterogeneous catalyst. [More]
Investigating Detergent Tablet Stability

Investigating Detergent Tablet Stability

Detergent packaging has undergone many changes during the past decade to address the constantly changing customer requirements and environmental concerns. Detergents in tablet form by directly compressing dry powders are one of the major advances in detergent packaging in the past 10 years. [More]
Kaiser’s RamanRxn3™ Analyzer for In-line Monitoring of Ethylene Vinyl Acetate Copolymer with Raman Spectroscopy

Kaiser’s RamanRxn3™ Analyzer for In-line Monitoring of Ethylene Vinyl Acetate Copolymer with Raman Spectroscopy

Ethylene vinyl acetate (EVA) copolymer, based on the fraction of two monomers, can be used in a myriad of applications. The polymer melt needs to be monitored during manufacture to have a polymeric product with consistent quality. [More]