Importance of Using Quadrupole for Best Results in Mass Spectrometry and Selecting Ions for an Experiment

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Quadrupole Mass Spectrometer Systems
Quadrupoles for Advanced Research


It is important to use the quadrupole that provides the best results. Whether users are sizing select ions for their experiment or using a quadrupole as a mass spectrometer analyzer.

Today, the 6 mm quadrupole has become the most common size due to the proliferation of quadrupole technology in the last 60 years. This is due to the low cost of developing the RF supplies that drive them. You will find 6 mm quadrupoles are being used in analytical laboratory systems like Residual Gas Analysis (RGA), GC/MS, and process analyzers. In a high performance research analyzer, the quadrupole size is the deciding factor on data quality.

Quadrupole Mass Spectrometer Systems

Mass range, transmission, and resolution are the main performance attributes for quadrupoles. Better transmission means lower detection limits and more signals for analysis. A higher transmission in an ion selection application means less time is taken to collect the required ions. Resolution allows users to view clear, individual peaks for similar mass ions, and in certain cases, down to less than 0.05 Daltons apart. As the quadrupole becomes large in a given RF power supply, the mass range is reduced while the resolution and transmission improve.

So how does mass range fit in? This fully depends on the user’s requirements. Once users decide their required mass range, they will always want to increase the size of the quadrupole in order to obtain the highest ion throughput and the best mass separation possible.

As soon as scientists decide to look beyond the 6 mm quadrupole mass spectrometer system (QMS), they would find it difficult to navigate the options for choosing the right system. Extrel now provides quadrupoles in three different sizes such as 6 mm, 9.5 mm and 19 mm. The company is known for delivering reliable and stabile RF power supply products. When these products are combined with the appropriate quadrupole, they provide an analyzer that is optimized for a specific experiment.

Quadrupoles for Advanced Research

Extrel has more than five decades of experience in delivering quadrupole systems for advanced research, and has an excellent reputation for quality and performance. The company’s application experts are available to help customers select the right system for their specific application needs.

This information has been sourced, reviewed and adapted from materials provided by Extrel CMS, LLC.

For more information on this source, please visit Extrel CMS, LLC.

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