The HMK-1601 Tablet Friability Tester from AimSizer Scientific is a type of Roche friabilator. This device helps to determine the friability of uncoated, compressed tablets in the pharmaceutical industry.
The tablets are first weighed and then placed into a drum with a specific internal diameter and depth. The drum is then rotated 100 times at the fixed rate of 25 rpm, and the tablets tumble.
This is followed by re-weighing the tablets and calculating the weight loss. Tablets that pass the test are those with no more than 1% weigh loss, and those that obviously broke, cleaved, or cracked failed the test.
The HMK-1601 friabilator is used to tests the resistance of uncoated tablets to the abrasion and shock that occurs during the shipping, packing, and manufacturing processes. It is possible for the uncoated tablets to be broken, abrasive, chipped or capped during these processes. Measurement of tablet friability supplements various other physical strength measurements such as tablet crushing strength.
HMK-1601 tablet friability apparatus is a friability test apparatus that meets the international standard USP, E.P. and JP.
The friability test is performed using a friability tester that uses a drum in USP specified internal diameter and depth of transparent synthetic polymer with internal surfaces that are polished.
The tablets tumble each time the drum turns by a curved projection in USP specified inside radius that expands from the middle of the drum to the outer wall. The drum is fixed to the horizontal axis of a device that rotates at USP specified rpm. At every single turn the tablets slide or roll onto each other or onto the drum, friable tablet (>1%) does not pass the test.
The main features of the HMK-1601 Tablet Friability Tester are as follows:
- Built-in timer
- Exact results
- Available for 1 or 2 test drums
- Rapid, safe and effortless operation
- Available with both abrasion drum and friability drum
- Variable speed 20 to 60 rpm and fixed speed 25 rpm available
- Available for switching leg for 10° adjustment
- JP, USP, and E.P. compliant by standardized and reproducible method
- One side of the drum is removable
- Transparent synthetic polymer with polished internal surfaces prevent static build-up