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Hemetek Develops Squeeze Force Tester for Ophthalmic Bottles

In evaluating a medication, ease of use is nearly as an important a factor as its effectiveness. Along with determining the correct dosage, medication developers need to determine whether or not its packaging will break or leak under normal usage and if too much finger strength is required by either the patient or care giver in administering it.

Difficulty in administrating a medication can lead to poor compliance which, in turn, can result in poor treatment results or further disease progression.

When testing plastic bottles used for medication, such factors as the rigidity of the plastic, length of the nib, viscosity of the medication, and the dimensions of the bottle are all influencers on the amount of force needed to properly administer the medication.

Hemetek Techno Instruments Pvt Ltd., a leading supplier of Chatillon force gauges and material test machines based in India, developed a squeeze force tester specifically for testing plastic ophthalmic bottles and introduced it at the P-MEC India Exhibition in 2015. It has since received impressive initial interest from the medical testing industry.

The tester was developed for an Indian manufacturer of ophthalmic squeeze bottles to test the squeezability of its plastic bottles. The manufacturer wanted to determine the force required to deliver the first drop from single dose bottles as well as the force required to deliver subsequent drops.

Using the Chatillon squeeze force tester, the manufacturer was able to determine the finger strength needed to squeeze different bottle designs made from a variety of plastic materials.
The tests were performed at 90 degrees to simulate assisted administration of the drop and at 45 degrees to simulate self-administration by the patient.

At the heart of the squeeze force testing system is the digital Chatillon DFS II force gauge that features a simple user interface, large full color display and offers accuracy better than 0.1% of full scale. Loads are displayed in ozf, gf, lbf, kgf and N units. The digital DFS II force gauge is used with a mounting plate along with universal fixtures to accommodate testing of ophthalmic bottles of various sizes.

The Chatillon squeeze force tester incorporates proprietary NEXYGEN DF testing software, which offers pre- and post-test analysis of test results displayed as easy-to-read graphs in a Windows®- based environment. Test results are presented in a spreadsheet format for analysis. Units of measure, fonts and titles are easily customized. Bluetooth connectivity allows for the wireless transfer of test results directly to a personal, laptop or handheld computer.

Chatillon force gauges are manufactured by AMETEK Test & Calibration Instruments (TCI), which offers a comprehensive range of materials testing equipment for plastics, wood, metals, rubber, textiles and packaging. It is a unit of AMETEK a leading global manufacturer of electronic instruments and electromechanical devices.


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