The HandExtruder is Genizer’s most compact liposome extruder. Its compact size and minimal dead volume have made it popular in academic and small laboratories.
HandExtruder and the additional black syringe pads. Image Credit: Genizer LLC
Researchers employ this device to achieve the desired size of liposomes or lipid nanoparticles, as particle size can significantly influence circulation time, uptake, and stability, all of which are critical factors in various applications of liposomes.
The affordability of the HandExtruder provides an accessible entry point for academics interested in liposome extrusion.
The HandExtruder has been referenced in academic research within the pharmaceutical field. For instance, one study utilized the HandExtruder with 200 nm membranes to produce liposomes for investigating cancer treatments (link).
In another study, the HandExtruder played a crucial role in preparing vaccination nanoparticles (link). Beyond pharmaceuticals, researchers across diverse fields, including agriculture (link) and protocell research (link), have incorporated the HandExtruder into their work.
During discussions with clients at trade shows, Genzier found that some users experienced discomfort when using the small syringe end for extended periods.
In response, they developed a more ergonomic solution. The Genizer team introduced syringe pads designed to increase the surface area in the palm, enhancing the ease with which researchers can size liposomes. These syringe pads are easily attachable and removable.
The liposome HandExtruder is low-cost, with minimal dead volume and temperature control. And now, comfortable syringe pads. Image Credit: Genizer LLC
This information has been sourced, reviewed and adapted from materials provided by Genizer LLC.
For more information on this source, please visit Genizer LLC.