DXR 2 Raman Microscope from Thermo Fisher Scientific

The DXRTM2 Raman Microscope from Thermo Fisher Scientific offers point and shoot Raman microscopy with superior sensitivity and spatial resolution for functional applications. This technology completely redefined the Raman microscope so that busy laboratory demands are met. This instrument family is reliable, usable and features high-performance.


The DXRTM 2 Raman Microscope is suited to:

  • Identification and characterization of small particles
  • High-resolution depth profiling and subsurface analysis of semi-opaque and transparent samples
  • Characterization of coatings, multi-layer laminates, thin films, inclusions and subsurface defects
  • Organic and inorganic samples - the wide spectral range with measurements down to 50cm-1 is of specific advantage for inorganics, which typically have bands at low frequencies
  • Molecular morphology characterization - ideal representation of carbon and silicon molecular backbones offers great differentiation of pharmaceutical and mineral polymorphs as well as differentiation of amorphous and crystalline forms of silicon and different carbon nanomaterials
  • Characterization of surface areas and subsurfaces are supported with x-y area maps and x-z maps
  • Measurements through glass and plastic packaging enables direct measurement through evidence bags, injectable ampules, and protective overcoatings
  • Remote sampling for samples that are too large to fit under the microscope, with optional fiber-optic probes


Main features of the DXRTM 2 Raman Microscope include:

  • Configurable GO button on instrument enables walk-up operation
  • All data collection, processing, and reporting steps can be stored so that a user can load a sample under the microscope, push a button, and have a report print out with no interaction with the computer
  • Supports surface-enhanced Raman scattering (SERS) measurements
  • Lasers, filters, and grating Smart modules all user exchangeable and can be shared with other DXR instruments
  • The microscope has been independently certified as class-1 laser safe
  • Laser is physically blocked from visual viewing path to prevent exposure to the eyes while viewing
  • Complete package for DQ/IQ/OQ/PQ validation is available including extensive documentation and automated software protocols
  • Omnic D/S software offers CFR 21 part 11 compliance
  • Automatic fluorescence correction available with all excitation lasers and research-quality Olympus viewing optics
  • Automatic intensity correction generates spectra that can be compared between instruments and different excitation lasers
  • Multidimensional wavelength calibration offers precise wavelength calibration across the entire spectral range
  • Proprietary Triplet spectrograph offers exceptional peak shape and maintains focus at all wavelengths
  • Software controlled switching between confocal and high-energy collection modes is enabled
  • Proprietary algorithm for automated cosmic ray rejection and high-quality laser line filters ensure artifact-free spectra
  • Laser Power Regulator enables active monitoring of laser power and ensures reproducible laser excitation power over the laser life and even after replacing lasers
  • Optimized gratings for each excitation laser avoid performance sacrifices of systems that share gratings for multiple excitation lasers
  • Proprietary autoalignment ensures system can be maintained in like-new condition
  • Proprietary Smart-backgrounds automatically remove CCD dark energy profile


The applications of the DXRTM 2 Raman Microscope include:

  • Pharmaceutical – polymorphs, particulate contaminants, and diffusion studies
  • Art Restoration/Conservation – identify and characterize pigments, resins, glazes, and inks
  • Solar – Silicon crystallinity; characterization of photovoltaic materials
  • Failure analysis – characterizing particulates and small features on surfaces
  • Nanotechnology – characterize graphene, CNTs, DLC coatings and other anostructures
  • Academic research – useful in material science, biological studies, and many applied research fields
  • Gemology – rapid ID of colored stones, distinguishing natural and synthetic diamonds, characterizing inclusions and adulterants
  • Archaeology – characterize horn, shell, bone, and ceramic artifacts
  • Polymers – inclusions and gel defects, weathering effects, tie layers in laminates, and crystallinity
  • Forensics – trace evidence and illicit drug identification

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