Berkeley Lab to Use LECO Citius LC-HRT for Research in Metabolomics

LECO Corporation has entered into an agreement with the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) for the development of metabolomic applications and tools.

Berkeley Lab’s Life Sciences Division will receive access to the LECO Citius™ LC-HRT (High Resolution TOFMS) for applied research in metabolomics. Designed for complex sample analysis, LECO’s HRT instrumentation provides acquisition speeds of up to 200 spectra/second, mass resolution up to 100,000 FWHM, and mass accuracy less than 1 ppm.

The research will be led by Dr. Trent Northen, a staff scientist with Berkeley Lab’s Life Sciences Division and with the Joint BioEnergy Institute (JBEI). Dr. Northen’s research aims to construct detailed models of cellular communities’ metabolism and energy through an integrated program of metabolite imaging and metabolomic analysis. This approach is being applied to understand the dynamics of microbial communities, as well as the metabolic drivers of breast cancer.

“For LECO, this collaboration is a wonderful opportunity to support the work of a leader in metabolomics, and to be part of the tradition of scientific excellence at Berkeley Lab,” said Dr. Jeff Patrick, Director of Marketed Technology, LECO Separation Science. “We believe this partnership will accelerate and facilitate the addressing of both biological and medical questions.”

About LECO Corporation

For more than 75 years, industries around the world have trusted LECO to deliver technologically advanced products and solutions. Today, that commitment continues with High Resolution Time-of-Flight Mass Spectrometry (TOFMS) for liquid and gas chromatography, as well as comprehensive two-dimensional gas chromatography (GCxGC), all featuring easy-to-use ChromaTOF® operating software. Product lines also include high-quality analytical instrumentation, metallography and optical equipment, and consumables. LECO has over 30 subsidiaries worldwide, with additional distributors authorized to sell or service LECO products to the rest of the world.

About Lawrence Berkeley National Laboratory

Lawrence Berkeley National Laboratory addresses the world’s most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab’s scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy’s Office of Science.


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