Posted in | Materials Analysis

Malvern Instruments to Exhibit Latest Biophysical Characterization Technology at Forum Labo & Biotech 2013 Conference in France

At Forum Labo & Biotech (4-7 June 2013, Paris, France) Malvern Panalytical will exhibit the latest materials and biophysical characterization technology and instrumentation, including Archimedes, the new Zetasizer Nano ZSP and an extended range of sample dispersion accessories for the Mastersizer 3000.

In addition to participating in the exposition, the company is also running a half-day user training course on particle size measurement by laser diffraction and size of nanoparticles by dynamic light scattering,  which is free of charge to Forum Labo attendees.

Among the exciting additions on the Malvern Panalytical booth this year is Archimedes, developed and designed by Affinity Biosensors and MIT in the USA, and now part of Malvern Panalytical’s rapidly growing portfolio of analytical tools for biopharmaceutical applications, and entered for an innovation award at the show.

The Zetasizer Nano ZSP is one of the advanced instruments on show on the Malvern Panalytical stand at Forum Labo. Credits: Malvern Panalytical.

Archimedes uses resonant mass measurement to detect and count particles in the size range 50 nm to 5 µm, and to measure particle mass and size. It is especially useful for characterizing protein aggregates in formulation or buffer and is uniquely positioned to quantitatively measure protein aggregates from 100 nm – 1 µm, the size range highlighted as of particular concern for immunogenicity and product safety in protein therapeutics.

Launched in September 2012, the new Zetasizer Nano ZSP has added unique protein measurement and novel microrheology capabilities to this established and market-leading range of dynamic light scattering (DLS) systems. Like other systems in the Zetasizer range, the Zetasizer Nano ZSP is a single, compact unit, but has unique performance specifications for both size and zeta potential measurement. One of the most significant new applications is the measurement of the zeta potential, or more precisely electrophoretic mobility, of proteins.

A protein mobility measurement package is included with the Zetasizer Nano ZSP instrument as standard. As well as the suite of new protein-specific features, the Zetasizer software enables a brand new type of measurement on the instrument – microrheology. This DLS-based optical technique allows rheological characterization of weakly-structured and highly strain-sensitive materials using only microliter sample volumes. Amongst its applications are measuring the viscosity of polymer and protein solutions and determining the onset of protein aggregation.

No show would be complete without the Mastersizer 3000 laser diffraction particle size analyzer, which is on display together with the latest sample dispersion accessories, the Hydro SM and Hydro EV. The Hydro SM is a cost effective wet sample dispersion unit designed for measuring samples in non-aqueous dispersants where solvent usage needs to be minimized. The Hydro EV is a unique dip-in wet sample dispersion unit that can be used with standard laboratory glassware and is suitable for a wide variety of dispersant volumes and particle size ranges.

About Malvern Panalytical

Malvern Panalytical provides the materials and biophysical characterization technology and expertise that enables scientists and engineers to understand and control the properties of dispersed systems. These systems range from proteins and polymers in solution, particle and nanoparticle suspensions and emulsions, through to sprays and aerosols, industrial bulk powders and high concentration slurries.

Used at all stages of research, development and manufacturing, Malvern Panalytical’s materials characterization instruments provide critical information that helps accelerate research and product development, enhance and maintain product quality and optimize process efficiency.

Our products reflect Malvern Panalytical’s drive to exploit the latest technological innovations and our commitment to maximizing the potential of established techniques. They are used by both industry and academia, in sectors ranging from pharmaceuticals and biopharmaceuticals to bulk chemicals, cement, plastics and polymers, energy and the environment.

Malvern Panalytical systems are used to measure particle size, particle shape, zeta potential, protein charge, molecular weight, mass, size and conformation, rheological properties and for chemical identification, advancing the understanding of dispersed systems across many different industries and applications.

Headquartered in Malvern Panalytical, UK, Malvern Panalytical has subsidiary organizations in all major European markets, North America, China, Japan and Korea, a joint venture in India, a global distributor network and applications laboratories around the world.

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