Reverse Engineering Pharmaceuticals Helps Fight Counterfeit Drugs

Chemical imaging specialists at Malvern Panalytical are demonstrating how data derived from reverse engineering of pharmaceutical tablets can aid the fight against counterfeit drugs. Using the SyNIRgi near infrared chemical imaging (NIRCI) system they have been able to collect data detailed enough to characterize the formulation and processes used to create individual dosages. Results can be compared to both the original manufacturer specifications and a database of known counterfeits.

 

 

An application note, entitled 'NIR chemical imaging for tablet deconstruction: A case study for solid dosage forms' outlines the methodology required to produce this level of information. 

SyNIRgi combines the species identification capabilities of conventional near infrared spectroscopy with digital imaging, to answer the questions 'what?', 'how much?' and 'where?'. Able to non-destructively analyze powders, granules and tablets of all shapes and sizes, SyNIRgi gives results in minutes.

Not only does it have clear applications in counterfeit detection and as a tool for Quality by Design, it also takes the guesswork out of formulation development, speeds up QA/QC and aids rapid troubleshooting in manufacturing. No sample preparation is needed, data acquisition speeds are high, and by simply changing an objective the system can be quickly configured for either microscopic or macroscopic imaging.

Citations

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Malvern Panalytical. (2021, March 09). Reverse Engineering Pharmaceuticals Helps Fight Counterfeit Drugs. AZoM. Retrieved on May 28, 2024 from https://www.azom.com/news.aspx?newsID=22752.

  • MLA

    Malvern Panalytical. "Reverse Engineering Pharmaceuticals Helps Fight Counterfeit Drugs". AZoM. 28 May 2024. <https://www.azom.com/news.aspx?newsID=22752>.

  • Chicago

    Malvern Panalytical. "Reverse Engineering Pharmaceuticals Helps Fight Counterfeit Drugs". AZoM. https://www.azom.com/news.aspx?newsID=22752. (accessed May 28, 2024).

  • Harvard

    Malvern Panalytical. 2021. Reverse Engineering Pharmaceuticals Helps Fight Counterfeit Drugs. AZoM, viewed 28 May 2024, https://www.azom.com/news.aspx?newsID=22752.

Tell Us What You Think

Do you have a review, update or anything you would like to add to this news story?

Leave your feedback
Your comment type
Submit

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.