Nanoplastic-Induced Protein Misfolding - A Submicron IR Study of Molecular Changes in Biological Systems

Nanoplastics (NPs) are being increasingly recognized as potential biological hazards, but their direct effects on molecular structure and cellular function remain poorly understood.

Image Credit: Photothermal Spectroscopy Corp

In this webinar, Assoc. Prof. Oxana Klementieva (Lund University) will present new findings based on her recent paper: Polystyrene nanoplastic exposure promotes amyloid misfolding and metabolic impairment at sublethal doses. A subcellular infrared imaging study.

This research shows how 200 nm polystyrene NPs can induce protein misfolding and impair cellular metabolism. Using submicron IR (Optical Photothermal Infrared, O-PTIR) spectroscopy, this work visualizes nanoscale biochemical changes inside cells without labels or dyes, revealing how nanoplastics act as active interfaces that alter function and protein structure, which is implicated in some neurodegenerative diseases.

Dr Mustafa Kansiz, Director of Product Management (Photothermal Spectroscopy Corp.) will provide a brief overview of submicron IR (O-PTIR) spectroscopy and application examples demonstrating how O-PTIR enables direct, label-free mapping of MPs/NPs and biomolecular changes in complex biological systems.

Click here to register

What You Will Learn

  • How NPs drive protein misfolding and amyloid-like changes
  • How sub-lethal exposure impacts cellular metabolism
  • How O-PTIR maps protein structure inside cells at submicron resolution
  • How particle–protein interactions can be directly observed in situ

Who Should Attend

  • Micro- and nanoplastics researchers
  • Toxicologists and health scientists
  • Neurodegeneration and protein aggregation researchers
  • Cell biologists and spectroscopy users

We look forward to seeing you there in Webinar!

Can’t join live? Register anyway, and we’ll send the recording.

See you there on Thursday, May 28, 2026 (Three time zones available) 

Speaker:

Dr Mustafa Kansiz

Director of Product Management
Photothermal Spectroscopy Corp

Guest Speaker:

Dr Oxana Klementieva

Associate professor
Lund University, Sweden

Register now

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