Presented by: Bill Warren and Neil J. Lander (Waters Corporation)
Presented Live: September 16, 2025
As GLP-1 receptor agonists (GLP-1RAs) continue to transform the therapy landscape for metabolic disorders, ensuring the integrity and quality of these complex molecules becomes increasingly important.
This webinar explores advanced analytical methodologies for determining critical quality attributes (CQAs), with an emphasis on Size-Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS) and Reversed-Phase Chromatography with Mass Spectrometry (RPC-MS).
Attendees will learn about SEC column selection for impurity profiling, the advantages of native vs. denaturing SEC for aggregation analysis, and the relative strengths of MALS and MS detection.
The webinar also includes a side-by-side comparison of liraglutide and semaglutide, highlighting how integrated data processes using Empower CDS with MALS may streamline complex studies while meeting compliance standards and product quality.
Empower CDS helps laboratories satisfy regulatory demands while increasing efficiency by providing built-in solutions for method standardization, safe data handling, and audit-trail integrity.
This webinar provides practical information and best practices for designing and monitoring GLP-1RAs utilizing Waters' end-to-end LC, column, detector, and software solutions.