Presented by: Udayabagya (Bud) Halim (Waters | Wyatt Technology)
Presented Live: October 15, 2025
GLP-1 receptor agonists (GLP-1RAs), which are now central to diabetes and weight management therapy, require precise and dependable analytical procedures throughout development, production, and quality control.
This webinar explores how light-scattering techniques, such as dynamic light scattering (DLS) and multi-angle light scattering (MALS), enable comprehensive assessment of critical quality attributes (CQAs).
The webinar also examines how MALS, combined with size-exclusion chromatography (SEC-MALS) under native and denaturing conditions, provides accurate, quantitative data on molar mass, size, aggregation, and oligomeric state, as well as their impact on colloidal stability.
Case studies will demonstrate the characterization of GLP-1 analogs such as liraglutide, semaglutide, and related peptides, with a focus on applications such as aggregation screening, impurity profiling, and stability analysis.
The session will cover how the latest Empower™ Chromatography Data System includes modern detectors for orthogonal characterization in QC procedures, ensuring secure and compliant data handling to enhance product integrity and regulatory compliance.