High-throughput dynamic light scattering (HT-DLS) and the automated DynaPro® Plate Reader III help in transforming nanoparticle and biotherapeutic development. The DynaPro outshines at high-throughput sizing and screening of biopharmaceutical and nanoparticle formulations to bring about novel workflows that cannot be attained with other DLS instruments.
The DynaPro® Plate Reader III offers a total solution in a standard well plate
- Optimize protein buffers
- Formulate nanoparticles
- Develop stable biopharmaceuticals
- Discover small-molecule and peptide drugs
Achieve the Complete Attribute Landscape
- Solubility
- Viscosity
- Molar mass (Mw)
- Size and size distributions (rh)
- Aggregation and stability indicators (Tonset, Tagg, Tm, A2, kD)
Fast, Accurate, Easy
- Measure from 4º to 85 ºC
- Film- or oil-based evaporation seal
- 21 CFR Part 11 compliant software
- Sample volume as low as 4 μL
- As sensitive as a cuvette-based DLS
- User friendly experiment design in Dynamics
- First and only A2 and Mw in a plate
- Infrared wavelength not susceptible to fluorescence
- Uses industry-standard 96, 384 or 1,536 microwell plates
Design High-throughput Experiments
Advantages
Comprehensive DLS experiments can be tackled and content-rich screening data can be explored like never before.
Weeks of Experiments within Just Hours
Biologics: Colloidal and Thermal Stability
The DynaPro Plate Reader III performs high-throughput screening of biotherapeutic candidates, in order to define multiple properties of a plateful of candidates and formulations. The below presents the analysis of monoclonal antibodies (mAbs) for thermal stability.
