HORIBA Instruments Acquires All Shares of MANTA Instruments

HORIBA develops, manufactures, and sells nanoparticle tracking analysis systems used in life-science, semiconductor manufacturing process and environmental process.

The latest model of MANTA’s nanoparticle tracking analysis systems, the ViewSizer® 3000, emits a laser beam at nanoparticles in Brownian motion*1 in a fluid to track them and, by means of image analysis, evaluates size distribution, number concentration, and the aggregation state of particles from 10 nanometers in size with high resolution. In the fluorescence mode, fluorescently labeled particles can be measured. This innovative instrument is expected to meet customer needs in the life science and pharmaceutical research markets, which require data on particle number concentration, as well as in the cosmetics, catalysis, and semiconductor markets, where measurement in the nanoregion is essential. The particle characterization instruments market, which MANTA’s ViewSizer 3000® belongs to, is estimated to reach 2.06 billion yen in 2019 and continue to expand at a compound average growth rate (CAGR) of 8.4% up to 2022 (Company data).

*1 Random motion of particles suspended in a liquid

Target Fields and Applications

  • Life science -> Aggregation/crystallization of proteins, research and development of exosomes, viruses, and antibody drugs
  • Agriculture and forestry, water, and home electronics -> Fine bubbles with antimicrobial and purifying properties
  • Semiconductor materials -> Production control of semiconductor wafer polish and quality control of semiconductor ultrapure water
  • Environment -> Quality monitoring and treatment of water (number of aquatic nanoparticles)
  • Pharmaceuticals, food, and cosmetics -> Particle  concentration control for the pharmaceutical industry,  ultra-low concentration samples.
  • Functional nanomaterials -> Catalyst materials and carbon nanotubes
  • Catalysts and rechargeable batteries -> Research, development, improvement, and quality control of new materials

Integration Timeline

After the completion of the acquisition process, MANTA’s development and production functions will be transferred to HORIBA Instruments, thus commencing the development of the next-generation model by capitalizing on HORIBA’s proprietary technologies. When combined with existing optical technologies, MANTA’s image processing technology is expected to contribute to in-vitro diagnostics, regenerative medicine, and research and development of biopharmaceuticals, in addition to particle measurement. HORIBA also plans to apply this advanced technology to CMP (chemical mechanical polishing) slurries in the semiconductor field and aquatic nanoparticle measurement in the environmental field.

MANTA’s ViewSizer® 3000 nanoparticle tracking analysis system

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