Ask an Expert! - Ensuring Sample Integrity During Zeta Potential Measurements

Electrophoretic light scattering (ELS) is a technique for measuring the zeta potential of particle dispersions and macromolecular solutions. Zeta potential is the surface charge that a particle or macromolecule has in a particular medium and can be used to predict dispersion stability and provide information on the surface chemistry of the sample under investigation.

For most applications, the measurement of zeta potential is routine. However, for certain samples which contain delicate material (e.g., proteins) or high ionic strength dispersants (e.g., physiological buffers), measurement can be more challenging. It is important to ensure that sample integrity is maintained during these measurements, and that results are accurate.  

In this webinar, we will discuss some practical tips, and discover how to set up measurements to ensure that sample integrity is not compromised when measuring delicate or challenging samples.

Whether you have questions about samples or sample preparation, setting up an experiment or performing an analysis, feel free to submit a question so that we can address the topics most important to you. There’s always more to learn, whether about setting up your measurements for quick batch processing, gaining confidence in the quality of your results, or presenting your data in the best format. 

For this webinar, we will assume you have watched the previous one on the same topic. Don't worry if you missed it the first time or can't remember it. Before you attend this webinar, please watch last year's introduction. You can find it here. 

Don’t forget to bring your questions or submit them by emailing [email protected]. (For inclusion in the webinar presentation, questions and data can be submitted up to 10 days upfront. There is also the opportunity to ask questions on the day.) 


  • Mike Kaszuba - Technical Support Manager

More Information: 

This webinar is part of our ongoing ‘Ask an expert’ webinar series. These live webinars are meant for students, researchers, and professors alike who want to sharpen their analytical methods, deepen their knowledge, or find out how to improve their data. 

We’ll provide extensive materials analysis information and answer your most frequently asked questions. In other words, it’s the ultimate way to improve your materials science research and engineering knowledge. 

It’s free to attend any of the classes. For a full overview of the 2022 program, click here

To watch any of last year’s webinars, take a look at the full program recordings here.

Who should attend? 

  • Anyone performing zeta potential measurements such as students, researchers, laboratory staff, and academics 

What will you learn? 

  • How and why electrophoretic light scattering is used
  • How to correctly prepare samples for zeta potential measurements
  • How to measure high conductivity samples to obtain accurate results

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