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Microfluidizer Offers Effective Cell Disruption

Analytik reports on how the School of Biological & Chemical Sciences at Queen Mary University, London (QMUL) has been using a LM20 Microfluidizer for cell disruption of a broad range of cell types including E. coli, Yeasts and Diatom.

The School of Biological and Chemical Sciences at QMUL (https://www.qmul.ac.uk/)  is one of the UK’s leading life science research departments, with a multi-disciplinary approach to teaching and research. QMUL research staff are actively engaged in a wide range of projects across the broad sweep of biological, chemical and psychological sciences.

We approached Analytik to find a replacement for a high-pressure homogeniser, from another manufacturer, which had been unreliable and failed to achieve sufficient lysis of our tough yeast cells even after very many passes. We selected the LM20 Microfluidizer not only because it efficiently lysed a broad range of cell types but also was incredibly simple and easy to use which is very important as many different people need to use the machine regularly. We also much appreciate the knowledgeable technical and applications support provided by Analytik which has enabled us to fully exploit the considerable capabilities of the LM20 Microfluidizer.

Petra Ungerer, Cell and Molecular Biology Laboratories Manager, QMUL

The LM20 Microfluidizer is a digitally controlled high pressure homogeniser performance optimised for small volumes. It maintains identical sample processing conditions, reliably producing the desired results, including uniform particle and droplet size reduction (often submicron), deagglomeration and high-yield cell disruption.

We were very pleased to have been selected by QMUL to supply a high-pressure homogeniser for their broad ranging cell disruption needs. In our experience it is now not necessary for biological scientists to accept limitations on the cell types that they can reliably and efficiently disrupt. Our LM20 Microfluidizer uniquely combines top performance, operational efficiency and ease of use for this important application.

Ian Laidlaw, Managing Director, Analytik


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