Posted in | Chemistry

Smithers Rapra Publishing Release Book on the Latest Advancements in Transient Gene Expression Technology

Smithers Rapra Publishing has announced the release of Update on Production of Recombinant Therapeutic Protein: Transient Gene Expression.

Over the past decade, the transient gene expression (TGE) technology platform has been actively pursued to produce a wide range of therapeutic proteins, monoclonal antibodies, and vaccines for mainly preclinical assessment, due to its short development times and low overall cost.

This book updates the latest advances in the field, with focusing on systematic description of the technology from cell lines, cell culture conditions, vector construction, expression strategy, current protocols, optimisation of the procedure, and potential for clinical application.

As a conclusion, the author foresees that therapeutic biopharmaceutics will be manufactured for clinical development using TGE technology in the near future because of its fast development time, good protein expression, acceptable quality of product and due to the progress which has been made in analytical methodology and process quality control.

The book summarises current TGE protocols, describes optimisation of the technology through the latest advances, and explores clinical applications of the technology. It gives the reader a good insight into the latest development and future application of the technology platform.

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