Jun 9 2010
Research and Markets(http://www.researchandmarkets.com/research/97f4b5/dynamic_combinator) has announced the addition of John Wiley and Sons Ltd's new report "Dynamic Combinatorial Chemistry: In Drug Discovery, Bioorganic Chemistry, and Materials Science" to their offering.
In a relatively short period, Dynamic Combinatorial Chemistry (DCC) has grown from proof-of-concept experiments in a few isolated labs to a broad conceptual framework with applications to an exceptional range of problems in molecular recognition, lead compound identification, catalyst design, nanotechnology, polymer science, and others.
Bringing together a group of respected experts, this overview explains how chemists can apply DCC and fragment-based library methods to lead generation for drug discovery and molecular recognition in bioorganic chemistry and materials science.
Chapters cover:
- Basic theory
- Approaches to binding in proteins and nucleic acids
- Molecular recognition
- Self-sorting
- Catalyst discovery
- Materials discovery
- Analytical chemistry challenges
A comprehensive, single-source reference about DCC methods and applications including aspects of fragment-based drug discovery, this is a core reference that will spark the development of new solutions and strategies for chemists building structure libraries and designing compounds and materials.
Key Topics Covered:
- Preface.
- Contributors.
- Chapter 1: Dynamic Combinatorial Chemistry: An Introduction (Benjamin L. Miller).
- Chapter 2: Protein-Directed Dynamic Combinatorial Chemistry (Michael F. Greaney and Venugopal T. Bhat).
- Chapter 3: Nucleic Acid-Targeted Dynamic Combinatorial Chemistry (Peter C. Gareiss and Benjamin L. Miller).
- Chapter 4: Complex Self-Sorting Systems (Soumyadip Ghosh and Lyle Isaacs).
- Chapter 5: Chiral Selection in DCC (Jennifer J. Becker and Michel R. Gagn).
- Chapter 6: Dynamic Combinatorial Resolution (Marcus Angelin, Rikard Larsson, Pornrapee Vongvilai, Morakot Sakulsombat, and Olof Ramstrm).
- Chapter 7: Dynamic Combinatorial Chemistry and Mass Spectrometry: A Combined Strategy for High Performance Lead Discovery (Sally-Ann Poulsen and Hoan Vu).
- Chapter 8: Dynamic Combinatorial Methods in Materials Science (Takeshi Maeda, Hideyuki Otsuka, and Atsushi Takahara).
- Index.
Source: http://www.researchandmarkets.com/