Analyzing RNA Protein Complexes with Solid State NMR
This video shows Prof. Dr. Teresa Carlomagno from BMWZ Institute, Leibniz University explaining the potential use of Bruker's Solid State NMR for studying RNA protein complexes. A new combination technique using solid state NMR and small angle neutron scattering is important to analyze the structure of RNA protein complexes.
NMR offers precise information about relative position of proteins in the complex, while small angle neutron scattering gives information about the shape of the complex. The combination technique provides better sensitivity and resolution for analyzing RNA proteins. In this way, NMR can be used along with other techniques like FRET, electron microscopy etc. The future of structural biology research lies in the combination of such different techniques.
Run Time – 4:22min