Studying Individual Brain Cells Using Mass Spectrometry

This video shows Professor Jonathan Sweedler from the University of Illinois, describing about using mass spectrometry for brain research.

The brain uses many different molecules. To find unusual cells and to characterize them, the measurements have to be moved down to individual cells. Single cell measurements depend on success of sampling. Technological advances in mass spectrometry can help characterize greater number of individual cells. Mass spectrometry can be combined with vibrational spectroscopy, and with high-resolution vibrational imaging of the brain, one can get more chemical information on the same cell. More information about the brain will help recognize the difference between healthy and the diseased brain. Mass spectrometry helps learn more about peptides, enzymes and other molecules that will lead to better understanding of brain diseases and will also help discover novel pharmacological targets.

Run Time – 3:44min

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