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Wyatt Technology, a business unit of Waters Corporation, develops instrumentation, software and techniques for the characterization of macromolecules and nanoparticles, in solution, based on light scattering and related technologies. The physical properties determined by Wyatt’s products include absolute molar mass of proteins, polymers and other macromolecules; size and charge (zeta potential); protein-protein and other biomolecular interactions; composition of conjugated proteins and co-polymers; and macromolecular conformation.
Wyatt’s product line includes instruments and software for:
Wyatt also offers, on a limited basis, sample analysis services utilizing its unique technologies.
Multivalent Binding Partners: Binding Affinity and Metacomplex Formation
Unbiased and Absolute Polyurethane Molar Mass Measurements with SEC-MALS
Making Flow Field-Flow Fractionation (FFF) Easier with Fixed-Height Channels
Real-Time Multi-Angle Light Scattering for PAT of Polysaccharide
Determining Chitosan Molar Mass with SEC-MALS
A Comprehensive View of the Characterisation of Exosomes
Measuring Polymers, Proteins with Online Viscometers
Using Online Multi-angle Light Scattering and Differential Viscometry to Characterize Hyaluronic Acid
Using UHP-SEC to Characterize Polymers with Light Scattering
Highlights in the Field of Natural Polymers
Selecting the Correct Chromatography Detector
The Diffusion Interaction Parameter (Kd) as an Indicator of Colloidal and Thermal Stability
Understanding Antibody and Viral Glycoprotein Interactions Using CG-MALS
Charge and Interaction Analysis for Predicting Antibody Formulation Stability
Coupling MALS and SAXS for Time-Resolved Studies of Biopolymeric Filamentous Networks Assembly: Fibrin Formation
Challenges of Nanoparticle Characterization and How to Overcome them with the Light Scattering Toolkit
High-Speed Process Monitoring with the UHP-SEC-MALS
Protein Quality Control in Surface Plasmon Resonance and Bio Layer Interferometry Screening Studies
Measuring Absolute Molar Mass in Ultra-High Performance Liquid Chromatography with µDAWN and Optilab UT-rEX
Evaluating Various Techniques for the Analysis of Branching Structure in Synthetic and Natural Polymers
Combining Molecular Weight and Net Charge to Differentiate Unmodified and Contaminated Heparin
Quantifying the Self-Association of Insulin at Neutral pH Using Composition-gradient Multi-Angle Light Scattering
Application of Column Chromatography (SEC/GPC) and MALS for Characterizing Monomers, Dimers, Hexamers and Aggregates of Insulin
Application of Refractive Index Detection for UHPLC to Identify and Quantitate Molecular Species of a Sample Source
Light Scattering Methodologies Developed for the Characterisation of Protein Aggregate Composition
Characterizing Key Parameters of Variation Between Batches of Heparin by Combining MALS, DLS and MP-PALS Techniques
Basic Principles of Applying Multi-Angle Light Scattering Technique for the Detection and Characterization of Molecular Structures in Synthetic and Natural Polymers
Absolute Characterization of HA Properties Using SEC-MALS, Differential Refractometry, and Differential Viscometry Instruments
Metacomplex Formation in the Hetero-Association of Multivalent Antigen and Bivalent Binding Partners Using CG-MALS
Using SEC-MALS Technology to Characterize Haemoglobin
Application of FFF-MALS-QELS to Characterise Liposome Size and Encapsulation
Wyatt Technology's Atlas for Mobility Measurements of High Salt Solutions
DynaPro NanoStar for Nano-particle and Macromolecular Analysis by Wyatt Technology
Optilab UT-rEX Differential Refractometer Technology for Ultra High Performance Liquid Chromatography
Wyatt DynaPro Dynamic Light Scattering (DLS) System for the Characterisation of Heterodimeric Protein Complex
Drug-Antibody Component Analysis Using ASTRA 6 Software Tool
Using Field Flow Fractionation to Obtain High Resolution Distributions of Nanoparticle Size and Zeta Potential
A Guide to Properly Measuring Zeta Potential and Particle Size for Challenging Samples Using Wyatt Technology's Mobius
Determining the Size and Conformation of Biopolymers, Synthetic Polymers, Proteins and Peptides
Commercializing Multi-Angle Light Scattering Instruments
Macromolecule and Nanoparticle Characterization
Wyatt Technology Announces Advances in Dynamic Light Scattering (DLS) Technology with Walk-up Measurements
Announcing the 2022 George E. Pake Award Recipient – Dr. Philip Wyatt
DynaPro Plate Reader III – Automated Biopharmaceutical and Nanoparticle Characterization
The Emerging Field of Gene Therapy with Adeno-Associated Viruses
ultraDAWN™ - Real-Time Product Attributes for Bioprocess Monitoring and Control
DynaPro Plate Reader Dynamic and Static Light Scattering Detector
ViscoStar Differential Viscometer for GPC
WyattQELS Dynamic Light Scattering Module
Eclipse™ Flow Field-Flow Fractionation System
Mobius Size and Zeta Potential Detector
Calypso Biomolecular Interaction Analysis System
DynaPro NanoStar II Dynamic Light Scattering Detector
Optilab Refractive Index Detector for HPLC/GPC
DAWN Multi-Angle Light Scattering (MALS) Detector
Upcycling Polyolefins into Value-Added Thermoplastics
Shining a Light on Conjugated Polymers with GPC-MALS
Expanding the Characterization Toolkit with FFF-MALS
Understanding Polymer Properties with Multi-Angle Light Scattering
Characterising of lentiviral & gammaretroviral vectors
Characterizing Polymers and Polymer Aggregates Using SEC-MALS
Solving SEC/GPC Limitations with Multi-Angle Light Scattering and Asymmetric-Flow Field-Flow Fractionation
Multi-Detector Asymmetric-Flow Field–Flow Fractionation for Nanoparticle Analysis in Complex Matrices
Determination of critical product parameters for proteins from research to production