The LC 6000 Liquid Chromatography System for Analytical Laboratories

The SCION LC 6000 liquid chromatograph is designed for outstanding long-term performance, ensuring trust in findings. This device is made for precise, reliable, and fast measurements, maximizing uptime and production while minimizing operating costs.

With a wide range of automation options, the HPLC will optimize operations, making the laboratory experience smoother and more efficient.

The liquid chromatograph delivers dependable, consistent results while compensating for variability and risk. The experienced team is committed to assisting users in determining the optimal HPLC setup for the lab’s requirements.

Excellent Detector Performance

The 6000 Series LC system features a variety of detectors, including an ultraviolet and diode-array detector, a fluorescence detector, and a refractive index detector, all designed for stability, accuracy, and sensitivity.

Low Volume Degassing Options

The low-volume degassing equipment shortens solvent purging time and minimizes the quantity of solvent required.

Plunger Wash

To prevent salt precipitation from the mobile phase. The SCION 6000 Series LC system can be fitted with an automatic plunger-washing mechanism to protect the pump seal and plunger.

Extra Large Solvent Cabinet

The SCION 6510 Organiser is intended to handle several liquids and can store bottles of various sizes to suit a range of uses.

Manual Injection Valve

A manual injector, rather than the 6210/6220 Autosampler, can be used in the 6000 Series for instructional or low-throughput applications. A manual valve provides excellent repeatability in circumstances when a single good outcome is required.

Superior Gradient Performance and Excellent Flow Rate Precision

The SCION 6100 Quaternary pump has a unique low-pressure mode, High Frequency Mode (HFM), which uses a proportioning valve's double-switching feature. HFM, combined with a high-speed, real-time feedback control system, significantly reduces liquid pulsation, improving gradient and retention time repeatability.

Excellent Injection Volume Precision and Ultra-Low Carry-Over

The high-precision syringe drive device enables precise injection volume measurement. Dead volume in the SCION 6210/6220 Autosampler flow route has been reduced. Syringe washing techniques and strict temperature control have resulted in a more accurate autosampler with less carryover.

Peltier-Based Heating and Cooling

The SCION 6310 Column Oven provides precise Peltier-based heating and cooling profiles, producing crisp peaks with good peak symmetry. The column oven can hold three 250 mm analytical columns along with a guard column.

Edinburgh Instruments can now provide a comprehensive product line of LC columns with our 6000 Series HPLC, starting immediately. A diverse range of base materials, diameters, functional groups, and particle sizes is now available to suit the majority of HPLC applications. For more demanding applications, the SCION 6320 column oven can accommodate three 400 mm or six 150 mm columns.

Compass CDs Control

The SCION LC 6000 HPLC system provides comprehensive support via CompassCDS, which includes full instrument control and automation, a complete suite of integration, calibration, and reporting capabilities, and full 21CFR11 compliance.

SCION Instruments LC6000 HPLC - Overview

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Oil and Gas

High Performance Liquid Chromatography is used extensively in the oil and gas sector.

The HPLC system has several major applications in the oil and gas industry, including:

  • Hydrocarbon analysis involves determining the content and quantity of hydrocarbons in crude oil and petroleum products. This analysis aids in determining the quality, purity, and conformity with regulatory norms
  • Contaminant detection involves identifying and quantifying impurities and pollutants that can affect the quality and performance of petroleum products. It helps to ensure compliance with environmental rules and product requirements
  • Additive analysis is the study of additives applied to petroleum products to improve their performance and stability. Accurate estimation of additive concentrations is critical for maintaining product quality and meeting industry standards
  • Residue analysis is used to identify and quantify pesticide, herbicide, and other chemical pollutants in crude oil and refined petroleum products. This study contributes to complying with safety and environmental laws
  • Quality control allows for the monitoring and verification of product parameters, including the detection and measurement of contaminants, ensuring that petroleum products satisfy industry standards and consumer expectations

Overall, high performance liquid chromatography provides essential analytical capabilities to the oil and gas sector, assisting with quality assurance, regulatory compliance, and assuring the safe and efficient production, processing, and distribution of petroleum products. With highly specialist analysers that adhere to ASTM, EN, ISO, IP, and GPA standards and procedures, users can be certain that the results will exceed regulatory criteria.

Chemical

HPLC systems are often utilized in the chemical industry for a variety of applications. Here are some important applications in which liquid chromatography is used:

  • Compound Analysis and Identification: used to conduct qualitative and quantitative analyses of chemical compounds in diverse samples. It assists in determining the presence of target chemicals
  • Quality Control: enables the evaluation of product purity, the identification of contaminants, and the verification of product requirements. HPLC helps to confirm that chemical products fulfill the necessary requirements and follow regulatory norms
  • Separation and Purification: Used to separate and purify complicated chemical combinations. It allows for the isolation of desirable chemicals, the elimination of contaminants, and the purification of products
  • Stability studies assess the deterioration and shelf life of chemical substances. It aids in the detection of degradation products, monitoring formulation stability, and determining the efficacy of preservatives and antioxidants
  • Process Monitoring is used to monitor chemical processes in real time and regulate them. It allows for the measurement of reaction progress, monitoring of intermediates and byproducts, and modification of reaction parameters
  • HPLC is a valuable technique in chemical research and development. It aids in the synthesis and analysis of new compounds, the characterization of reaction products, and the improvement of chemical processes

To summarize, liquid chromatography is a flexible technology utilized extensively in the chemical industry. Its capacity to produce precise and consistent findings makes it a desirable tool in a variety of chemical applications.

Pharmaceutical

High-performance liquid chromatography is a key method in the pharmaceutical industry, with applications ranging from drug research to quality control and regulatory compliance. Here are some major uses of HPLC in the pharmaceutical industry:

  • Drug Compound Analysis: HPLC allows for the separation, identification, and quantification of compounds in drug formulations, assuring their purity, potency, and regulatory compliance
  • Formulation Development: investigate the compatibility and stability of drug compounds with excipients, monitor drug component degradation and interaction, and determine formulation dissolution patterns
  • Bioanalytical Analysis: HPLC allows for the measurement of drugs and metabolites in biological fluids, which aids in bioavailability research, therapeutic drug monitoring, and drug-drug interaction evaluation
  • Dissolution testing evaluates the release rate of medicines from solid dosage forms such as tablets and capsules. HPLC measures drug dissolution patterns, ensuring that the drug is delivered in a controlled and consistent way

Liquid chromatography is crucial in many aspects of pharmaceutical development. Its accuracy, sensitivity, and capacity to handle complicated samples make it an essential instrument in the pharmaceutical industry.

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Environmental

High-performance liquid chromatography is often used in the environmental industry to analyze and monitor contaminants. Here are some major uses of HPLC in the environmental industry:

  • Water quality analysis involves examining water samples for the presence of organic pollutants such as pesticides, herbicides, pharmaceuticals, industrial chemicals, and their metabolites
  • Soil and Sediment Analysis: helps in monitoring remediation operations, assessing possible hazards to ecosystems, and evaluating the quality of soil and sediment
  • To identify and describe contaminants discovered at pollution sites, use environmental forensics
  • Wastewater analysis: making it possible to identify and measure heavy metals, organic pollutants, and other contaminants from municipal and industrial wastewater treatment facilities

Food

The food sector uses high-performance liquid chromatography for a number of tasks, including nutritional analysis, safety testing, and quality control.

  • Food additive analysis is the process of analyzing and quantifying food additives, such as colorants, sweeteners, antioxidants, preservatives, and flavor enhancers, to make sure that food items meet legal requirements and are accurately labeled with information about their presence and content
  • Pesticide and Residue Analysis: to find and measure pesticide residues in food samples, ensuring that agricultural products meet safety standards and are free of dangerous pesticide levels
  • Vitamin and Nutrient Analysis: It supports nutritional labeling and manufacturer claims by helping to evaluate the nutritional content and quality of foods
  • Flavor and Aroma Analysis: It helps ensure consistency and authenticity in food items by helping to understand the composition and quality of flavors, such as volatile chemicals responsible for aroma

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