NanoDrop Lite Plus Spectrophotometers

The Thermo ScientificTM NanoDropTM Lite Plus Microvolume Spectrophotometer, the entry-level companion to the full-featured Thermo ScientificTM NanoDropTM One/OneC and NanoDrop Eight Spectrophotometers, allows users to quickly and conveniently measure sample concentration and purity ratios.

This instrument provides rapid, precise measurements in an easy-to-use, affordable package, but has fewer capabilities than the premium versions.

The NanoDrop Lite Plus Spectrophotometer is an excellent teaching tool as well as a quality control tool in busy research laboratories. Using proven NanoDrop technology, it is possible to measure pure DNA, RNA and protein concentrations up to 30 Abs and determine important A260/A280 and A260/A230 purity ratios.

Source: Thermo Fisher Scientific – Materials & Structural Analysis

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Absorbance Accuracy 3% at 0.97 A, 302 nm, 23 ± 2C° Absorbance expressed as Abs/mm measured at 25 °C
Absorbance Range 0.04–30 Abs (10 mm equivalent)
Certifications/Compliance UL/CSA and CE
Compatibility Local Control Only
Concentration 1,500 ng/µL (1,200 ng/µL) dsDNA (RNA) 45 mg/mL (21 mg/mL) BSA (lgG)
Connections USB 2.0 Port
Depth (Metric) 22 cm
Description NanoDrop Lite Plus Spectrophotometer (no printer)
Detection Limits 2.0 ng/µL (1.6 ng/µL) dsDNA (RNA) 0.06 mg/mL (0.03 mg/mL) BSA (lgG)
Detector Type 2048-element CMOS linear image sensor
Display LCD Touchscreen
Light Source Xenon flashlamp
Type UV Microvolume Spectrophotometer
Voltage 100/240 V
Wavelength Range 230 nm, 260 nm, 280 nm
Footprint 27 x 22 x 22 cm (0.6 x 8.7 x 8.7 in); W x D X H
For Use With (Application) Nucleic Acid Quantification, DNA Quantification, RNA Quantification, Protein Quantification
Height (Metric) 22 cm
Material Sample Pedestal - 303 stainless steel and quartz fiber
Measurement Time ≤ 5 seconds
No. of Samples 1
Pathlength 1.0 mm and 0.2 mm (auto adjust)
Power Consumption 18 W (standby < 3 Watts)
Printer Included No
Processor Standalone control with data export via USB Flash Drive
Sample Volume (Metric) 1 - 2 µL
Spectral Resolution ≤ 1.8 nm (FWHM at Hg 254 nm)
System Requirements Standalone control with data export via USB Flash Drive
Warranty One year
Wavelength Accuracy ± 1 nm
Wavelength Repeatability Typical: 0.002 A (1.0 mm path) or 1%CV, whichever is greater. (SD of 20 individual measurements at 0.74 Abs)
Weight (English) 6.0 lbs (without printer)
Weight (Metric) 2.7 kg (without printer)
Width (Metric) 27 cm
Unit Size Each


The NanoDrop Lite Plus Spectrophotometer is designed for routine nucleic acid and protein assays with only 1–2 µL of sample volume. This cutting-edge sample-retention technology removes the need to dilute extremely concentrated samples, allowing for simple measurements.

Simply pipette the sample onto the optical measuring pedestal, measure it and wipe it clean with a lint-free wipe. The NanoDrop Lite Plus Spectrophotometer takes up very little room on the benchtop, thanks to its tiny design and built-in controls and software.

The NanoDrop Lite Plus Spectrophotometer is the main instrument for simple microvolume measurements, thanks to its easy user interface and current industrial style. Even if budgets are limited, the lab can benefit from a NanoDrop.

Confidence in Results

  • Up to 30 Abs of pure DNA, RNA and protein content are measured
    • RNA concentrations of up to 1,200 ng/µL
    • dsDNA concentrations of up to 1,500 ng/µL
    • BS up to 45 mg/mL
  • Calculates the critical purity ratios of A260/A280 and A260/A230
  • Measurements that are considered standard
  • Touchscreen control built-in
  • Fast, precise readings from only 1–2 µL — no waste, preserves valuable samples
  • Surface tension is used to hold the sample in place, therefore no cuvettes or costly consumables are required
  • Storage and transmission of data
  • Budget-friendly — stretch tight budgets
  • There is no need for a computer
  • A freezer-compatible label printer is provided as an option (not included)
  • The last 1,000 measurements are recorded locally, and data may be exported to a USB device
  • The interface is easy to use
  • It fits on any lab bench and is ready for the next experiment

Reach Goals

  • Academic research labs — help users conduct the study and publish the groundbreaking results
  • Biotech start-ups — increase the speed with which new goods are developed
  • Academic teaching — on an industry-leading instrument, teach students molecular biology fundamentals and experimental methodologies

Video Credit: Thermo Fisher Scientific – Materials & Structural Analysis

NanoDrop Lite Plus Spectrophotometers

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