NanoDrop™ Ultra Microvolume Spectrophotometers and Fluorometers for Research and QC Applications

The Thermo Scientific^™ NanoDrop^™ Ultra Spectrophotometer and Fluorometers enable scientists to measure and evaluate nucleic acids and proteins with greater accuracy, speed, and dependability.

The next generation of microvolume detection is represented by the Thermo Scientific^™ NanoDrop^™ Ultra Spectrophotometers and Fluorometers. With sample quantities as little as 1.0 μL, these state-of-the-art devices provide remarkable sensitivity and accuracy for protein and nucleic acid detection.

Numerous disciplines, including genomics, proteomics, molecular biology, biotechnology, pharmaceutical, and life sciences research, can benefit from the NanoDrop Ultra's streamlined procedures. It offers unmatched accuracy, effectiveness, and dependability in a small package.

With the Thermo Scientific^™ NanoDrop^™ Ultra Microvolume UV-Vis Spectrophotometers and Fluorometers, users can grasp sample quality like never before and prevent expensive setbacks in the process. Every instrument has cutting-edge Thermo Scientific^™ Acclaro^™ Sample Intelligence technology for enhanced measurement precision and contamination detection.

Before deciding to use samples in downstream applications, get full-spectral data by quantifying and qualifying DNA, RNA, and protein samples in a matter of seconds using just 1–2 μL. For further versatility, versions that work with cuvettes are also offered.

The NanoDrop Ultra spectrophotometers' large, high-resolution 10.1-inch touch screen interface and compact form make them ideal for users seeking convenience and flexibility.

With an enhanced algorithm, the optional Acclaro Pro software - compatible with the NanoDrop Ultra instruments - unlocks increased accuracy for highly concentrated samples. Compared to the popular NanoDrop 2000/2000c and NanoDrop One/One^C Spectrophotometers, this next-generation NanoDrop single channel instrument has better hardware and software features.

Acclaro Sample Intelligence Technology

Acclaro technology provides precise quantitative assessments while improving user comprehension of sample quality. Early contamination detection can save days of debugging and save downstream applications from failing.

• Contaminant detection and analysis: Enables users to accurately identify, measure, and reduce contaminants by providing a thorough assessment of sample purity AND correcting sample absorbance. Researchers, scientists, and experts in disciplines including agriculture, plant biology, microbiology, and genetic engineering have access to plant and bacterial DNA and RNA differentiations
• Sample integrity insight - sends real-time notifications when bubbles are found in the sample, which may otherwise result in erroneous readings
• Reliable precision is ensured by the use of an embedded sensor and computerized image analysis

Tools to Aid in 21 CFR Part 11 Compliance

Optional Thermo Scientific^™ SciVault^™ 2 software installs on either the instrument or a companion PC and provides labs with capabilities to comply with US FDA 21 CFR Part 11.

• Compliance made easy: SciVault 2 integrates into the NanoDrop Ultra software user interface to handle user accounts, digital signatures, and audit logs.
• On-board options: Software can be executed directly on the local instrument using on-board user account management, or users can link the instrument to the domain and manage the Windows accounts.
• Centralized solution: Installing SciVault 2 software on a central computer allows users to monitor audit logs and manage permissions for several NanoDrop Ultra equipment located in various laboratories.

Streamlined Workflow

• Completely integrated qPCR recipe calculator: let the software do the math for the user by adding the preferred kit or using the built-in library. Depending on the concentration of the sample, the qPCR recipe calculator recommends how to set up the reaction.
• Auto-Measure and Auto-Blank features: Instantaneous measurements that take place when the pedestal arm is down can simplify multi-sample processing. One tap on the screen can activate or deactivate these features.

Advanced Connectivity for Data Storage, Printing and Sharing

• Export to the cloud: Export data straight to well-known cloud storage platforms like Thermo Fisher Connect, Google Drive, and Microsoft OneDrive.
• Direct LIMS integration: Send data directly into the LIMS with the assistance of an integrated RESTful API.
• Easy data-to-printer options: Use Wi-Fi, Ethernet, or a USB printer to print the results straight from the NanoDrop Ultra device; use the Nanodrop Ultra PC Control software to print exported data from the PC.
• Data User’s Way: Before exporting the data file, make sure it satisfies any downstream requirements by customizing and previewing its contents.

Accuracy Beyond Expectations with the Acclaro Pro Software

New versions of the most widely used measurement applications that are unlocked from the factory are included in this optional software package, which offers ±5 % error over the absorbance dynamic range.

• Accurate high concentration measurements: Absorbance measurements within 5 % error up to 550 Abs (10 mm equivalent) up to 400 mg/mL IgG or 18,000 ng/μL
• Quick dilution-free process: Take three measurements on the pedestal in two minutes with this quick, dilution-free method
• Improved calibration: Bundled purchases receive an extra calibration from the manufacturer to ensure the instrument is calibrated for outstanding accuracy in Acclaro Pro applications

Source: Thermo Fisher Scientific