The ROYALPROBE™ HFX is the world’s first liquid NMR probe that allows switching between single-tune and dual-tune modes on a high-frequency coil.
The ROYALPROBE™ HFX operates in single tune mode and performs as well as the current standard JEOL NMR ROYALPROBE in terms of sensitivity and pulse widths.
To simplify the spectral assignments of contemporary complex fluorine-containing compounds for the pharmaceutical and polymer industries, a wide range of sophisticated 1H and 19F NMR experiments, such as 1H {19F}, 19F {1H}, X{1H,19F}, and numerous unique X{1H,19F} correlation experiments, are possible when the HFX probe is operated in dual tune mode.
To conduct these sophisticated H, F, and X experiments, a standard 2-channel ECZ spectrometer can be used. The low-frequency coil can be tuned to any nucleus between 31P and 15N.
Single Tune. Image Credit: JEOL USA, Inc.
Dual Tune. Image Credit: JEOL USA, Inc.
Fluticasone Propionate
A new degree of adaptability for fluorinated compound NMR analysis, which is common in many novel pharmaceutical products.
Image Credit: JEOL USA, Inc.